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Cefuroxime Axetil I.P eq.to Anhydrous Cefuroxime 500 mg+Potassium Clavulanate Diluted I.P. eq. to Clavulanic Acid 125 mg
An oral prodrug of the bactericidal cefuroxime antibiotics.
Effective against wide range of gram positive and gram negative organisms including beta lactamase producing strains.
Possess the distinctive properties of a broad spectrum antibiotics and β-lactamase inhibitor.
Protect cefuroxime from degradation by β-lactamase enzyme.
Effectively extends the spectrum to include many bacteria normally resistant to cefuroxime and other β-lactam antibiotic.
Combination of Cefuroxime and clavulanic acid provides a solution for treatment of bacterial infections caused by β-lactam resistant bacteria.
Cefuroxime axetil/clavulanic acid 500 mg/kg twice daily is more effective as amoxicillin 500 mg/kg three times daily in the treatment of pneuminia and produces fewer gastroinrestinal adverse effects,particulary diarrhea.
Cefuroxime/clavulanic acid,"follow-on" therapy produces clinical and bacteriological efficacy equivalent to that of amoxicillin/clavulanic acid,with the advantage ot twice daily oral administration.